Contributor: Gordon K. Klintworth
Myoclonic epilepsy is form of epilepsy characterized by the clonic fibrillary twitching of muscle fibers. It is a prominent clinical feature of Lafora disease, MERRF,  myoclonic epilepsy-encephalopathy-lacic and stroke-like episodes, and sulfocysteinuria. It also occurs in GM1-gangliosidosis type III.  The three polysaccharide storage diseases that produce Lafora bodies are neurological disorders. One causes myoclonic epilepsy, one produces bulbar signs, one is a motor neuron defect that progresses to tetraparesis and peripheral neuropathy [neuropathy - peripheral].