Contributor: Gordon K. Klintworth
Angiolipoma microthromboticum (familial angiolipomatosis, OMIM #206550) is a familial condition in which large subcutaeous angiolipomas occur in multiple locations (wrists, knees, ankles). The tumors recur after subtotal excision. The bones near affected joints are deformed and muscles at those sites manifest hypotrophy. The condition was first described in 1980 by Hapnes et al. and differs from the non-familial angiolipoma in which a solitary tumor appears in early adulthood. Familial angiolipomatosis may be the same as familial lipomatosis.