Contributor: Gordon K. Klintworth
Amebiasis is an important protozoal infection in parts of the world where it is endemic. Entamoeba histolytica is ingested from contaminated water and food in an encysted form. The organism escapes digestion until it lodges in the mucosa of the intestine, where the cyst wall dissolves and trophozoites form. Some are excreted with the feces to potentially infect other individuals; other amebae invade the intestinal wall. The predominant manifestation of amebiasis is dysentery due to colonic amebiasis, but the most frequent complication is an amebic liver abcess. An amebic abscess may perforate through the diaphram and cause empyema and a lung abscess. Peritonitis is an important cause of mortality. Hematogenous spread of Entamoeba histolytica is rare and ocular involvement isquestinonable as there are no histologically substantiated reports. Clinical observations allude to a maculopathy in which a transparent 'cyst' in the region of the posterior pole which was surrounded by retinal hemorrhage [hemorrhage - retina] and pigment disturbance. Anterior uveitis [uveitis - anterior] is a rare and presumptive.